As the Federal Reserve seems set to hold interest rates steady and the global growth outlook trends downward, investors will have to continue adjusting to the new normal. While times of adjustment and uncertainty provide investors with great opportunities, it's essential to ask the right questions: What are the steps to success for adapting portfolios to political and economic uncertainty? Has the timid pause in U.S. interest-rate hikes initiated the end of monetary tightening? And where can investors find pockets of opportunity, and what sectors and sovereigns should be deemed underweight given valuation and short-term political risks?