Pandemic-driven expansion in virtual care revealed the potential of homes as hubs for health. The spectrum of opportunities is rapidly growing—from the now-familiar telehealth appointment to cutting-edge passive monitoring technologies that can collect and transmit physiologic data and information about well-being to providers and caregivers. Projections estimate that up to $250 billion in US health-care spending could shift to virtual care. As record numbers of health plans and systems develop technology partnerships and acquire startups for the delivery of home-based clinical care, the lines between conventional health-care delivery and home-based care are blurring. Panelists will look at how we can build on this momentum to improve systems of care as we look to the future.