Global Conference 2017
Associate Director, Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins
Dr. Topalian is a physician-scientist whose studies of anti-tumor immunity have been foundational in developing cancer immunotherapy. She received her medical and scientific training at Tufts University School of Medicine, Thomas Jefferson University Hospital, and the National Cancer Institute. She joined the Johns Hopkins Kimmel Cancer Center in 2006 as the inaugural director of its melanoma program. Her current research focuses on manipulating "immune checkpoints" such as PD-1 in cancer therapy, discovering biomarkers predicting response and resistance, and developing effective treatment combinations. Dr. Topalian's work is widely recognized: She was named one of Nature's 10 in 2014, and received the Karnofsky Award from ASCO in 2015 and the Taubman Prize in 2016 for landmark discoveries in cancer immunotherapy. Her work has opened new avenues of scientific investigation and has established immunotherapy as a pillar of oncology.